Simparica Trio

What is Simparica Trio?

Simparica Trio is a veterinary antiparasitic medication intended exclusively for dogs. It is available as an oral chewable tablet that is generally well accepted due to its palatable flavour. Its key feature is its combined formulation, which includes three well-recognized active ingredients: sarolaner, moxidectin, and pyrantel.
This combination allows simultaneous action against multiple types of parasites with a single monthly treatment. Sarolaner targets external parasites, while moxidectin and pyrantel provide protection against various internal worms. Simparica Trio simplifies preventive care by reducing the need for multiple medications.
Widely used in veterinary protocols across Canada, Simparica Trio is designed to provide comprehensive protection when prescribed and administered according to veterinary recommendations.

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What is Simparica Trio used for?

Simparica Trio is used to protect dogs against fleas and ticks, while also treating and preventing certain internal worm infestations. It helps control common intestinal worms and contributes to the prevention of parasitic diseases that can affect a dog’s overall health.
By rapidly eliminating fleas, Simparica Trio helps reduce itching, discomfort, and associated skin problems. Its action against ticks helps limit exposure to certain tick-borne diseases.
Thanks to its broad spectrum of activity, Simparica Trio is particularly suitable for dogs with active lifestyles or those living in environments where parasite exposure is common, whether in urban or rural areas of Quebec.

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Dosage

Simparica Trio dosage depends strictly on the dog’s weight. It is essential to use the presentation corresponding to your dog’s weight range to ensure optimal effectiveness and safe use.
Simparica Trio is available in several weight-based presentations:

• 1.3 to 2.5 kg
• 2.6 to 5 kg
• 5.1 to 10 kg
• 10.1 to 20 kg
• 20.1 to 40 kg
• 40.1 to 60 kg

Each tablet contains precise concentrations of sarolaner, moxidectin, and pyrantel suited to the indicated weight range. Tablets must not be split and should not be used in dogs whose weight does not match the selected presentation. Your veterinarian will determine the appropriate dosage at the time of prescription.

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How and how often should I give Simparica Trio to my pet?

Simparica Trio is administered orally as a chewable tablet. It may be given directly as a treat or with a small amount of food if needed. Its palatable formulation generally makes administration easy, even for selective dogs.
The dosing frequency is monthly. One tablet should be given once per month to maintain continuous protection against both external and internal parasites. Choosing a fixed date each month is recommended to ensure consistent prevention and avoid missed doses.
Simparica Trio may be given with or without food. Always follow your veterinarian’s recommendations, especially if your dog is receiving other medications or has specific health conditions.

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What are the side effects and precautions associated with Simparica Trio?

Simparica Trio is generally well tolerated by most dogs when used according to veterinary recommendations, but mild and temporary side effects may occasionally occur.
Possible effects may include:

• mild digestive disturbances such as vomiting, diarrhea, or temporary loss of appetite
• temporary fatigue
• rare skin reactions

It is important to follow age and weight guidelines. Drug interactions may be possible, which is why informing your veterinarian of all treatments or supplements your dog is receiving is essential before starting Simparica Trio.

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