Fluoxetine

What is Fluoxetine?

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the availability of serotonin in the brain, a neurotransmitter involved in mood regulation and behaviour.
In animals, fluoxetine is used to treat certain anxiety and compulsive disorders when these conditions are persistent or negatively affect quality of life.

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What is Fluoxetine used for?

Fluoxetine is prescribed in dogs and cats for:

• chronic anxiety disorders
• compulsive behaviours
• anxiety-related aggression, under veterinary supervision
• separation anxiety, depending on the case

It is often combined with behavioural interventions to improve long-term outcomes.

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Dosage

Fluoxetine is available in oral capsule form in the following strengths:

• 10 mg
• 20 mg

The strength and quantity prescribed are determined by the veterinarian based on the species, body weight, and condition being treated.

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How and how often should I give Fluoxetine to my pet?

Fluoxetine is administered orally once daily.
It may be given with or without food.
Important considerations:

• onset of action is gradual, often taking several weeks
• consistent daily administration is essential
• long-term treatment should not be stopped abruptly

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What are the side effects and precautions associated with Fluoxetine?

Fluoxetine is generally well tolerated, but mild and temporary side effects may occur:

• decreased appetite
• lethargy or agitation
• digestive upset

Important precautions:

• risk of serotonin syndrome if combined with other serotonergic medications
• always inform your veterinarian of any other treatments
• discontinuation should be gradual and supervised

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